[Eoas-seminar] [Seminar-announce] Scientific Computing Colloquium with Leo Liu

[eoas-seminar at lists.fsu.edu]

"Decoding Heart Attacks and Strokes with Supercomputing and AI"

Leo Liu
Assistant Professor,
Chemical and Biomedical Engineering,
FAMU-FSU College of Engineering

Please feel free to forward/share this invitation with other groups/disciplines that might be interested in this talk/topic. All are welcome to attend.

NOTE: In-person attendance is requested in our 499 Dirac Science Library (DSL) Seminar Room. Zoom access is intended for external (non-departmental) participants only.

https://fsu.zoom.us/j/94273595552

Meeting # 942 7359 5552

🎦 Colloquium recordings will be made available here, https://www.sc.fsu.edu/colloquium<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.sc.fsu.edu%2Fcolloquium&data=05%7C02%7Csc-seminar-announce%40lists.fsu.edu%7C94e9322d9a734c21764b08dd70927f31%7Ca36450ebdb0642a78d1b026719f701e3%7C0%7C0%7C638790496668387990%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=%2FBngMIqiM3sOyRBnSkzLXYsI5IlWs84%2FRD%2Fa7Uqn%2BrY%3D&reserved=0>

Wednesday, Apr 2, 2025, Schedule:

* 3:00 to 3:30 PM Eastern Time (US and Canada)
☕ Nespresso & Teatime - 417 DSL Commons

* 3:30 to 4:30 PM Eastern Time (US and Canada)
🕟 Colloquium - 499 DSL Seminar Room

Abstract:
Heart attacks and strokes cause 1/3 of death in the modern world, which stem from a process called arterial thrombosis where clot forms abruptly in a narrowed artery obstructing blood flow. Current anti-thrombotic pharmaceuticals targeting biochemistry remain largely ineffective while leading to excessive bleeding risks. Our recent studies have led to evidence showing thrombosis is primarily controlled by a biophysical process of cells and proteins aggregating through high-shear hemodynamics. Decoding the biophysical mechanisms of arterial thrombosis in multiscale can lead to novel preventive strategies for successful longevity. In this colloquium talk, I will cover how we develop multiscale computational models suitable for driving first-principle based understanding of arterial thrombosis at multiple scales spanning from molecular, cellular to tissue levels. I will show how we combine multiscale computation as well as AI on in silico supercomputing chips and whole blood experiments on in vitro fluidic chips to form a powerful engine to drive scientific discovery. I will also discuss how novel treatment, and potential medical devices may be inspired from the unconventional biophysics predicted by our in silico and in vitro models.



Additional colloquium details can be found here,
https://www.sc.fsu.edu/news-and-events/colloquium/1867-colloquium-with-leo-liu-2025-04-02<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.sc.fsu.edu%2Fnews-and-events%2Fcolloquium%2F1867-colloquium-with-leo-liu-2025-04-02&data=05%7C02%7Csc-seminar-announce%40lists.fsu.edu%7C94e9322d9a734c21764b08dd70927f31%7Ca36450ebdb0642a78d1b026719f701e3%7C0%7C0%7C638790496668415254%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=qy10uE5f5vwgQb4l%2FprZ1n%2FggmoyLDaNkLmaWTmYUro%3D&reserved=0>
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