Weekly Funding Opportunities

Tue Mar 12 10:09:04 EDT 2019

2019 Atlanta Research Data Center Project Proposal Grant<https://atlantardc.files.wordpress.com/2019/02/proposal-1.pdf>
ARDC will fund project development grant proposals of up to $15,000 that will lead to research inside the Atlanta Federal Statistical Research Data Center. The ARDC houses demographic, economic, and health microdata (on individuals and firms) collected by the Federal government. Examples of the data available can be found here:
https://www.census.gov/about/adrm/fsrdc/federal_partners.html
Due April 5, 2019. Med-RA deadline to receive draft documents: March 22.

Next Generation Multipurpose Prevention Technologies (NGM) (R01 Clinical Trial Optional)<https://grants.nih.gov/grants/guide/pa-files/PAR-19-209.html>
The objective of this Funding Opportunity Announcement (FOA) is to support the development of new and innovative on-demand, event -driven and long-acting systemic and non-systemic multipurpose prevention technologies (MPT). It supports development of MPTs that prevent HIV infection and pregnancy (hormonal and non-hormonal methods); sexually transmitted infections (STI) and pregnancy, and (HIV/STI) and non-HIV STI MPTs in cis and trans males and females of all ages. Applications for MPT development may involve pharmacokinetic (PK), pharmacodynamic (PD), safety and, drug-drug interactions (DDI) studies using drug development and formulation science supported by animal model testing. Also supported are biobehavioral and behavioral/social studies to identify MPT user-desired rheological and biophysical factors (look, feel, effectiveness, safety and duration of action) and other behavioral/social factors that could promote increased MPT adoption and use.
Due May 6, 2019; May 6, 2020; and May 6, 2021. Deadline for Med-RA to receive draft documents: April 18.

Functional Target Validation for Alzheimer's Disease-Related Dementias (ADRDs) (UG3/UH3 Clinical Trial Not Allowed)<https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-19-015.html>
This FOA invites applications that propose the comprehensive functional validation of newly identified therapeutic target candidates for Alzheimer's Disease-Related Dementias (ADRD).  This FOA seeks to promote critical target validation approaches to help de-risk subsequent translational research and accelerate the advancement of novel therapies for ADRD. Target(s) or molecular pathway(s) to be considered for validation must have been already identified using tissue expression or genetic data generated in human samples. In its initial phase, this FOA provides support for up to two years (UG3 stage) for the development of customized technologies, models, and protocols to modulate the expression or activity of target candidate(s) in cells and/or tissues and monitor their functional biological consequences in in vitro or in vivo disease models.  Upon demonstration of technical feasibilities, a second phase (UH3 stage) will carefully and reproducibly measure and cross-validate the impact of the target modulation in different modalities across collaborating laboratories using the NIH rigor and reproducibility guidelines. Applicants responding to this FOA must address objectives for both the UG3 and UH3 phases and are expected to have a substantial collaborative effort between independent laboratories.
This FOA is not specific for any one or group within the ADRD spectrum of disorders. Disorders covered in these applications are frontotemporal degeneration (FTD), Lewy body dementias (LBD; including dementia with Lewy bodies [DLB]), Parkinson disease dementia (PDD), vascular contributions to cognitive impairment and dementia (VCID), and mixed dementias including the associated diagnostic challenges of multiple etiology dementias (MED).
Due May 6, 2019. Deadline for Med-RA to receive draft documents: April 18.

Decision Making and Human Behavior: Russell Sage Foundation Special Initiative<http://www.russellsage.org/funding/decision-making-and-human-behavior-context>
The Russell Sage Foundation's (RSF) special initiative on Decision Making and Human Behavior in Context will support innovative research on decision making across the social sciences that examines causes, consequences, processes, or context from a behavioral or alternative perspective. We seek to support a wide range of research on decision-making in context by scholars in psychology, political science, sociology, and other social science fields who are pursuing questions consistent with the aims of the Foundation.
This initiative will support research proposals from multiple methodological perspectives that will further our understanding of decision making processes and human behavior in the contexts of work, race, ethnicity, immigration, and social inequality, broadly conceived, in the U.S. Priority will be given to research related to our core programs<http://www.russellsage.org/programs> and other special initiatives<http://www.russellsage.org/special-initiatives>. Limited consideration will be given to projects that test well-established behavioral effects without examining the overarching context or the underlying mechanisms.
Research in this area is expanding rapidly. RSF is open to a range of questions consistent with its mission, and has a particular interest in the following research areas:
Biases and Misperceptions: An important contribution of behavioral science has been to uncover the role that biases play in decision making and behavior across multiple contexts. RSF is interested in studies examining implicit and explicit biases in employment, criminal, judicial, political, educational, and other important settings. To what extent and how do conscious and unconscious biases and misperceptions affect decisions and behaviors? What are the consequences of these actions?
Motivations and Incentives: Individuals respond to incentives, and to a broad array of social, political, psychological, and cultural motivations. RSF is interested in supporting research on motivated decision making and behavior that has consequences for social, economic and political inequalities. To what extent and how do motivations (e.g., sense of belonging, group identity, self-improvement, etc.) affect behavior and decisions related to wellbeing, mobility, or political participation? What role can collective deliberation play? What kinds of motivations are subject to change or interventions?
Habits and Behavior Change: A great deal of human behavior is not openly motivated, in the sense that it is habitual, intuitive, taken-for-granted, or otherwise not reflective. This kind of behavior can be a challenge for those seeking changes related to social, economic and political inequalities. How are socio-economically consequential habits formed and changed? To what extent does group membership affect the process? What are the limits of nudges and similar interventions that seek to modify the choice architecture involved in important decisions?
Affect and Emotions: Emotions shape people’s decision making and behavior, both consciously and subconsciously. The role of affect or emotions can be especially important to understand among powerful decision-makers. What role do emotions play in social, economic, political and legal decisions and behaviors? To what extent are the consequences for human welfare and related policies beneficial or detrimental? To what extent and how can detrimental effects be countered?
Networks and Contexts: Many decisions are made not in isolation, but with the help of social networks, whose members may be turned to for information, advice, support, or other needs. Networks also influence the way many such decisions are made and have been shown to be important in the context of the job search, college enrollment, voting, other topics relevant to mobility, poverty, and inequality. To what extent and how do contexts and networks—their structure and composition—affect decisions and behavior? To what extent and how do neighborhoods, organizations, and other contexts in which people form and maintain networks shape these processes?
Letter of inquiry due May 23, 2019 and August 19, 2019. Deadline for Med-RA to receive draft documents for May deadline: May 9.

Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)<https://grants.nih.gov/grants/guide/pa-files/PAR-19-207.html>
The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Outreach. This is a broad category of activities that emphasizes the dissemination of biomedical, behavioral, and clinical research findings from research on alcohol and other substance use to health professionals engaged in direct patient care and clinical service delivery. Specifically, this FOA will support projects designed to engage practicing health care professionals in education about current and emerging knowledge derived from scientific research on the neurobiology, epidemiology, prevention, and/or treatment of alcohol and other substance use disorders and related health conditions. Outreach activities should include strategies appropriate for engaging practicing health professionals in meaningful, actionable education about the current research on addictive disorders and state-of-the-art methods for detection, prevention, and treatment.
For the purpose of this FOA, “health care professional” is broadly defined to include a variety of licensed/credentialed health care providers, therapists, and allied professionals who provide direct patient care in general or specialty practice settings. Examples include but are not limited to physicians and nurses in primary care, general medical settings, emergency departments and trauma centers; medical staff in hepatology practices; nurses, social workers, and therapists in public health clinics, schools, child welfare, and criminal justice settings; pharmacists; medical staff in infectious disease clinics; and health professionals in other settings in which patients with alcohol or other substance use issues are likely to seek and receive services (including services unrelated to substance use). This FOA focuses on health care professionals who have completed their formal education – i.e., the outreach activities should be designed to reach beyond medical school and other traditional (pre-certification) classroom training into clinics and other settings where health professionals routinely encounter patients who could benefit from alcohol and other substance use screening and intervention. Such activities could include the development of short courses or computer-based educational tools, but should also consider other innovative strategies to educate practicing health professionals about current and emerging research findings, screening tools, preventive and treatment interventions, and best practices for population care management.
Standard dates apply. Expires September 8, 2020. Deadline for Med-RA to receive draft documents for May 25, 2019 deadline: May 13.

Next Generation Networks for Neuroscience<https://www.nsf.gov/pubs/2019/nsf19563/nsf19563.htm>
Understanding how behavior emerges from the dynamic patterns of electrical and chemical activity of brain circuits is universally recognized as one of the great, unsolved mysteries of science. Advances in recent decades have elucidated how individual elements of the nervous system and brain relate to specific behaviors and cognitive processes. However, there remains much to discover to attain a comprehensive understanding of how the healthy brain functions, specifically, the general principles underlying how cognition and behavior relate to the brain’s structural organization and dynamic activities, how the brain interacts with its environment, and how brains maintain their functionality over time. Achieving an understanding of brain structure and function that spans levels of organization, spatial and temporal scales, and the diversity of species requires an international, transdisciplinary collaborative effort to not only integrate discipline-specific ideas and approaches but also extend them to stimulate new discoveries, and innovative concepts, theories, and methodologies.

The objective of this phase of the NeuroNex Program is the establishment of distributed, international research networks that build on existing global investments in neurotechnologies to address overarching questions in neuroscience. The creation of such global research networks of excellence will foster international cooperation by seeding close interactions between a wide array of organizations across the world, as well as creating links and articulating alliances between multiple recently launched international brain projects. The potential transformative advances in neuroscience stemming from this activity will have profound scientific and societal impacts. The goal of this solicitation is to support collaborative networks (approximately 15 to 20 investigators in each network) comprised of international teams of disciplinarily diverse experimentalists, theorists, and research resource (including technology and cyberinfrastructure) developers working on a common foundational question in neuroscience. It is anticipated that these international networks will enable experimentation, analysis, and discovery in neuroscience at scales much larger than currently possible. This interdisciplinary, international program is one element of NSF’s broader effort directed at Understanding the Brain, a multi-year activity that includes NSF’s participation in the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (https://www.nsf.gov/brain/) and the phased approach to develop a research infrastructure for neuroscience as outlined in the Dear Colleague Letter NSF 16-047<https://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf16047>. The need for a program that helps neuroscientists collect, standardize, manage, and analyze the large amounts of data that result from research attempting to understand how the brain functions has been recognized by stakeholders in the scientific community and by the U.S. Congress in the American Innovation and Competitiveness Act (AICA) of 2017. The NSF and international partner agencies envision a connected portfolio of transformative, integrative projects that leverage existing global investments in neurotechnologies and create synergistic links across domestic and international investigators and communities, yielding novel ways of tackling the challenges of understanding the brain in action and in context.
Preliminary proposals due June 14, 2019. Deadline for Med-RA to receive draft documents: May 31.

Geroscience Approaches to Alzheimer’s Disease (R21 / R01 Clinical Trial Not Allowed)
R21<https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-20-014.html>
R01<https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-20-013.html>
These Funding Opportunity Announcements (FOAs) invite applications proposing research on the specific role of aging biology in the development, etiology, and treatment of Alzheimer’s disease. Aging is by far the main risk factor for most chronic diseases, a fact recognized by the field of geroscience. Recent advances in the fields of basic aging biology and geroscience now allow researchers to address mechanistically the role of aging in Alzheimer’s disease. Applications that make use of geroscience principles and test the role of different hallmarks of aging biology are specifically appropriate, while those focused solely on aging biology, or solely on Alzheimer’s disease will be deemed nonresponsive to these FOAs.
Due July 2, 2019. Deadline for Med-RA to receive draft documents: June 18.

To search for additional funding opportunities, please visit CoM’s unofficial funding opportunities blog<https://urldefense.proofpoint.com/v2/url?u=https-3A__fsucomgrants.wordpress.com_&d=DwMGaQ&c=HPMtquzZjKY31rtkyGRFnQ&r=EXkFPz4CfHp2YvDR6s1e2OHGNt7ixTIGEDylKw2SIo1FQ8O9soOgOzmn5ZTHU62o&m=-WQkPIXZLCgXlX-d14DY8B-SG-GvP9FZHr_Gv8sUuTQ&s=ErAzzubGxiJsWCKGnlFjfXV6980C-DCl-AxzFLHMVYQ&e=>.

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