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<p class="MsoNormal"><span style="color:#1F497D">Hi Panos/All:<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D">Thanks for letting me know. I am copying other ISL affiliates who may have an interest in the OAIC, and the clinical trial implementation FOA that you mention below.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D">Folks: for those interested in the OAIC opportunity, please fill out the poll at the following:
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><a href="http://whenisgood.net/dk3a557" target="_blank">http://whenisgood.net/dk3a557</a><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D">and I’ll determine the best meeting time and schedule a room where we can meet.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D">Best, Neil<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
<div>
<p class="MsoNormal"><span style="color:#282828">Neil Charness, Ph.D., William G. Chase Professor of Psychology<br>
Director, Institute for Successful Longevity </span><a href="http://www.isl.fsu.edu/"><span style="color:blue">www.isl.fsu.edu</span></a><span style="color:#282828"><br>
Department of Psychology, Florida State University<br>
1107 West Call Street, Tallahassee, Florida, USA 32306-4301<br>
Phone (office): 850-644-6686; Fax: 850-644-7739<br>
E-mail: </span><a href="mailto:charness@psy.fsu.edu"><span style="color:blue">charness@psy.fsu.edu</span></a><span style="color:#282828">;
</span><a href="http://www.psy.fsu.edu/~charness/"><span style="color:blue">http://www.psy.fsu.edu/~charness/</span></a><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black"> <o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black">Please Note:<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black">Due to Florida’s very broad public records law, most written business communications to or from FSU staff and/or any public college or university employee are public records, available to the public and media upon
request. Therefore, this e-mail communication may be subject to public disclosure.<o:p></o:p></span></p>
</div>
<p class="MsoNormal"><span style="color:#1F497D"><o:p> </o:p></span></p>
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<div style="border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0in 0in 0in">
<p class="MsoNormal"><b>From:</b> Panagiotis Koutakis <pkoutakis@fsu.edu> <br>
<b>Sent:</b> Thursday, July 11, 2019 12:15 PM<br>
<b>To:</b> Neil Charness <charness@psy.fsu.edu><br>
<b>Cc:</b> Lynn Panton <lpanton@fsu.edu>; Charalambos Konstantinou <konstantinou@caps.fsu.edu><br>
<b>Subject:</b> RE: Claude D. Pepper Older Americans Independence Centers (P30)<o:p></o:p></p>
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</div>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Dr. Charness,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I’m interested in forming a team for this program announcement (<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_rfa-2Dfiles_RFA-2DAG-2D20-2D019.html&d=DwMGaQ&c=HPMtquzZjKY31rtkyGRFnQ&r=CYRsm9C_r32RIuYi11MWPRPWKJe6CyxUDAD8OIZdiDs&m=4mb9j78yGIhy5yXDrhPmaNHCU74jC8u2OOIi9NUGwQQ&s=qkUSM68NhH48lOTmvmawpk3z_fL9ZMwIjkAv9mXKt-Y&e="><span style="font-family:"Arial",sans-serif">https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-20-019.html</span></a><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif">)</span></span>.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I want also to form a team for the NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required) -
<a href="https://grants.nih.gov/grants/guide/pa-files/PAR-19-302.html">https://grants.nih.gov/grants/guide/pa-files/PAR-19-302.html</a>. I already have two more sites that are willing to work with me and I think ISL needs to be involved on this.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Many thanks,<o:p></o:p></p>
<p class="MsoNormal">Panos<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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</v:shape><![endif]--><![if !vml]><img width="144" height="144" style="width:1.5in;height:1.5in" src="cid:image003.png@01D537E6.1D2753A0" align="left" hspace="12" v:shapes="Picture_x0020_1"><![endif]><span style="font-family:"Arial",sans-serif">Panagiotis
Koutakis, MS, PhD<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Assistant Professor<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Nutrition, Food and Exercise Sciences<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Director of Clinical Skeletal Muscle Physiology and Biochemistry Laboratory</span>
<span style="font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">428 Sandels Building (office)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">4014 William Johnston Building (</span><a href="https://humansciences.fsu.edu/csmpbl/"><span style="font-family:"Arial",sans-serif">laboratory</span></a><span style="font-family:"Arial",sans-serif">)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Florida State University<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Tallahassee, Florida 32306<o:p></o:p></span></p>
<p class="MsoNormal"><a href="mailto:pkoutakis@fsu.edu"><span style="font-family:"Arial",sans-serif">pkoutakis@fsu.edu</span></a><span style="font-family:"Arial",sans-serif"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><u><span style="font-family:"Arial",sans-serif;color:#0563C1"><o:p><span style="text-decoration:none"> </span></o:p></span></u></p>
<p class="MsoNormal"><o:p> </o:p></p>
<div>
<div style="border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0in 0in 0in">
<p class="MsoNormal"><b>From:</b> Isl <<a href="mailto:isl-bounces@lists.fsu.edu">isl-bounces@lists.fsu.edu</a>>
<b>On Behalf Of </b>Neil Charness via Isl<br>
<b>Sent:</b> Monday, June 17, 2019 2:06 PM<br>
<b>To:</b> ISL-affiliates <<a href="mailto:isl@lists.fsu.edu">isl@lists.fsu.edu</a>><br>
<b>Subject:</b> [Isl] Claude D. Pepper Older Americans Independence Centers (P30)<o:p></o:p></p>
</div>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Hi Folks:<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Below is the OAIC announcement, with a deadline of 10/2/2019. Cognitive and Behavioral and Social Science themes are NOT acceptable as a focus, though researchers from those areas can be involved. Please read the FOA (below) carefully
for eligibility issues. If there is interest in forming a team to go after this FOA, please reply to me and I’ll try to organize a meeting.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Best, Neil<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif">Claude D. Pepper Older Americans Independence Centers (P30 Clinical Trial Optional)<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">NIH/National Institute on Aging<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">RFA-AG-20-109<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">$4.75 million<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">5 years<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">posted 06/05/19<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">application 10/02/19<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">expires 10/03/19<o:p></o:p></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black"><o:p><span style="text-decoration:none"> </span></o:p></span></span></p>
<p class="MsoNormal"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__grants.nih.gov_grants_guide_rfa-2Dfiles_RFA-2DAG-2D20-2D019.html&d=DwMGaQ&c=HPMtquzZjKY31rtkyGRFnQ&r=CYRsm9C_r32RIuYi11MWPRPWKJe6CyxUDAD8OIZdiDs&m=4mb9j78yGIhy5yXDrhPmaNHCU74jC8u2OOIi9NUGwQQ&s=qkUSM68NhH48lOTmvmawpk3z_fL9ZMwIjkAv9mXKt-Y&e="><span style="font-family:"Arial",sans-serif">https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-20-019.html</span></a><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif"><o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black"><o:p><span style="text-decoration:none"> </span></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><b><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Research Objectives<o:p></o:p></span></b></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">The Claude D. Pepper Older American Independence Centers (OAIC) program was established in honor of the late Representative to establish
centers of excellence in research and research education to increase scientific knowledge leading to better ways to maintain or restore independence in older persons.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">The OAIC awards are designed to develop or strengthen awardee institutions’ programs that focus on and sustain progress in a key area
of aging research. Applicants should identify an area of focus in which progress could contribute to greater independence for substantial populations of older persons and offer opportunities for education in aging research. This area of focus should be a common
theme around which all proposed OAIC activities are organized. NIA's expectation is that an OAIC, in a given area of focus, will:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Provide intellectual leadership and innovation;<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Facilitate and develop novel multidisciplinary and interdisciplinary research strategies;<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Stimulate incorporation of emerging technologies, methods, and scientific advances into research designs, as appropriate;<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Provide research education for future leaders in geriatric research;<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Stimulate translation between basic and clinical research (e.g., research to develop or test interventions or diagnostic
tests based on new findings from basic aging research or other basic research or studies to improve understanding of mechanisms contributing to clinical or functional findings);<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Promote translation of clinical research findings into practice in relevant healthcare settings (see also "Health
Services Research as an Area of Focus" below);<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Collaborate substantially with other OAICs on multi-center projects such as integrating data systems, supporting multi-center
observational studies, and providing infrastructure to support multi-site clinical trials, including pragmatic trials;<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Interface where possible with the NIA Research Centers Collaborative Network (RCCN) and other NIA-funded programs
and centers (e.g., Resource Centers for Minority Aging Research (RCMARs), Centers on the Demography and Economics of Aging, Edward R. Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging, Alzheimer's Disease Centers (ADCs),
Nathan Shock Centers);<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Leverage institutional resources, including other NIH-supported programs and centers, to achieve the OAIC's aims with
efficiency; and<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Serve as a source of advice and collaboration to other investigators locally and on a large scale regarding technology,
methodology, analysis, or other expertise.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><b><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Area of Focus<o:p></o:p></span></b></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">To achieve the objectives listed above, each OAIC should promote a sustained research program in an area of focus through which the
Center will accomplish the innovation, leadership, collaboration, and research education functions described above. It is crucial to the design of an OAIC to identify an important research area to be addressed, to specify the goals to be achieved within the
five-year OAIC award period, to provide a plan to reach these goals, and to outline a method to evaluate progress toward these goals during the course of the OAIC award. The selection of core activities (see below) should follow from these considerations.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">An OAIC may select an area of research focus from a broad range of topics, including but not limited to:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Aging–related issues concerning a specific condition contributing to loss of independence in older persons (e.g.,
role of aging changes in the etiology of the condition; special issues in the diagnosis, treatment, or prevention of the condition in old age; complications, disability, or symptoms from the condition found principally in older persons).<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Causes, assessment, prevention, and treatment (including rehabilitation) of a specific type of disability in older
persons.<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Causes, prevention, and treatment of geriatric syndromes (e.g., sarcopenia, falls, incontinence) that are related
to multiple pathologies and/or disabilities.<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Specific aging-related physiologic changes, other risk factors, and/or interventions (e.g., physical activity) that
affect risk for multiple conditions or disabilities in old age.<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Interactions of multiple diseases, disabilities, and interventions (e.g., medications) in older persons and their
relationship to risk of morbidity, progression of disability, and efficacy of prevention or treatment strategies.<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l0 level1 lfo4">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Factors contributing to amelioration or delay of multiple deleterious aging changes by modulating risk factors or
fundamental aging mechanisms.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">In general, each research focus described above has the potential for a wide range of developmental and infrastructural activities
that are likely to be interdependent and synergistic. Thus, an OAIC strategy of selecting several key activities that address its area of focus may have unique benefits.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">As the level of funding for individual OAICs is unlikely to allow such a set of activities for more than one focus area, applicants
are strongly encouraged to select an area in which their strengths allow their OAIC to fulfill NIA's goal for the OAIC program and to direct their proposed OAIC activities toward that research area, while also ensuring that opportunities exist for collaboration
among other OAICs and other NIA programs and centers. The total impact of an OAIC's activities on progress in the selected field(s) should be a major criterion in selection of the focus area and will be a major criterion in peer review and program evaluation.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">To capitalize on important new research opportunities within their institutions, OAICs may also support a limited amount of activity
in their cores on topics other than those in their area of focus (see below). Applicants who anticipate providing such support should propose a system for identifying these opportunities and needs and for selecting core activities to address them.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><b><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Cognitive and Behavioral/Social Research as an Area of Focus.</span></b></span><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">
Cognitive or behavioral/social research should not be the major focus of an OAIC, as these areas are more appropriate for other NIA programs that also use the Center mechanism. However, where appropriate, OAICs are encouraged to support a multidisciplinary
approach that includes research in these areas as they relate to the theme or focus of the OAIC.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><b><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Health Services Research as an Area of Focus.</span></b></span><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">
Research to determine effects of organizational or operational patterns of health practices or services, or the use of new or different types of healthcare providers, is generally appropriate for an OAIC or a component of an OAIC if it meets the following
two criteria, in addition to the criteria above that exclude the major focus on cognitive and behavioral/social research:<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">1. The research is designed to obtain new knowledge about a) the effects of interventions or healthcare practices that clearly specify
what will be done for, or by, the individuals treated by these interventions or practices; or b) the validity or predictive value of diagnostic or assessment techniques that clearly specify what will be measured in individuals. Examples of interventions or
diagnostic strategies that may meet this criterion include:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l4 level1 lfo6">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">New drug or hormonal intervention protocols that may require a new organizational strategy to deliver them<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l4 level1 lfo6">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Disability prevention strategies based on application of treatment algorithms<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l4 level1 lfo6">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Structured physical activity programs<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l4 level1 lfo6">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">New diagnostic measures for an age-related condition (e.g., tests for diastolic dysfunction)<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l4 level1 lfo6">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Determining validity or predictive value of a functional assessment algorithm<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">2. The research is designed to determine health or risk-factor effects relating to outcomes that are primarily clinical or functional
(other than cognitive) in the individuals treated by the intervention or practice. Examples of outcomes include:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l2 level1 lfo8">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Disease and risk-factor outcomes, including diet and physical activity<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l2 level1 lfo8">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Functional outcomes<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l2 level1 lfo8">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Physiologic outcomes<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Research to determine effects of organizational or operational patterns of health practices or services, or the use of new or different
types of healthcare providers, would generally not be appropriate as a principal focus of an OAIC or OAIC component if either of the following two criteria were met:<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">1. The research is neither designed to obtain new knowledge about a) the effects of interventions that clearly specify what will be
done for, or by, the individuals treated by the intervention or practice, nor b) the validity or predictive value of diagnostic or assessment techniques that specify what will be measured in individuals. Examples of diagnostic or intervention research that
would generally be considered inappropriate as a principal focus for an OAIC or component of an OAIC include:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l3 level1 lfo10">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Testing effects of a geriatric assessment unit or other new health care service, without both a) specification of
the assessment protocol, criteria for deciding on appropriate treatment, a protocol for implementing treatment, and an adequate design to evaluate effects of these specific elements; and b) a design adequate to determine the effects of these specific components.<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l3 level1 lfo10">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Testing the effects of adding a new type of health professional (e.g., pharmacist) to a hospital service without both
a) specification of the change in specific diagnostic or intervention procedures that would be implemented, and b) a design adequate to determine the effects of these specific changes.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">2. The research is not adequately designed to determine health or risk-factor effects relating to outcomes that are primarily clinical
or functional (other than cognitive) in the individuals treated by the intervention or practice; for example:<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l5 level1 lfo12">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Research designed to determine effects only on healthcare providers' behavior (e g., time spent per patient or number
of diagnostic tests performed).<o:p></o:p></span></span></p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:-.25in;mso-list:l5 level1 lfo12">
<![if !supportLists]><span class="MsoHyperlink"><span style="font-family:Symbol;color:black;text-decoration:none"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span></span><![endif]><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Research designed to determine effects only on patients' behavior (e.g., adherence to a set of dietary guidelines).<o:p></o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><b><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Additional Guidance<o:p></o:p></span></b></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black;text-decoration:none">Applicants are strongly encouraged to visit the NIA OAIC webpage for additional guidance, recommended page formats, and answers to
frequently asked questions.</span></span><span class="MsoHyperlink"><span style="font-family:"Arial",sans-serif;color:black"><o:p></o:p></span></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="color:#282828">Neil Charness, Ph.D., William G. Chase Professor of Psychology<br>
Director, Institute for Successful Longevity </span><a href="http://www.isl.fsu.edu/"><span style="color:blue">www.isl.fsu.edu</span></a><span style="color:#282828"><br>
Department of Psychology, Florida State University<br>
1107 West Call Street, Tallahassee, Florida, USA 32306-4301<br>
Phone (office): 850-644-6686; Fax: 850-644-7739<br>
E-mail: </span><a href="mailto:charness@psy.fsu.edu"><span style="color:blue">charness@psy.fsu.edu</span></a><span style="color:#282828">;
</span><a href="http://www.psy.fsu.edu/~charness/"><span style="color:blue">http://www.psy.fsu.edu/~charness/</span></a><span style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black"> <o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black">Please Note:<o:p></o:p></span></p>
<p class="MsoNormal"><span style="color:black">Due to Florida’s very broad public records law, most written business communications to or from FSU staff and/or any public college or university employee are public records, available to the public and media upon
request. Therefore, this e-mail communication may be subject to public disclosure.<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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